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The impact of whole genome duplications on the human gene regulatory networks

This work studies the effects of the two rounds of Whole Genome Duplication (WGD) at the origin of the vertebrate lineage on the architecture of the human gene regulatory networks. We integrate information on transcriptional regulation, miRNA regulation, and protein-protein interactions to comparati...

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Detalles Bibliográficos
Autores principales: Mottes, Francesco, Villa, Chiara, Osella, Matteo, Caselle, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675932/
https://www.ncbi.nlm.nih.gov/pubmed/34871317
http://dx.doi.org/10.1371/journal.pcbi.1009638