Benznidazole Anti-Inflammatory Effects in Murine Cardiomyocytes and Macrophages Are Mediated by Class I PI3Kδ

Benznidazole (Bzl), the drug of choice in many countries for the treatment of Chagas disease, leads to parasite clearance in the early stages of infection and contributes to immunomodulation. In addition to its parasiticidal effect, Bzl inhibits the NF-κB pathway. In this regard, we have previously...

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Detalles Bibliográficos
Autores principales: Cevey, Ágata C., Mascolo, Paula D., Penas, Federico N., Pieralisi, Azul V., Sequeyra, Aldana S., Mirkin, Gerardo A., Goren, Nora B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675942/
https://www.ncbi.nlm.nih.gov/pubmed/34925364
http://dx.doi.org/10.3389/fimmu.2021.782891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675942/
https://www.ncbi.nlm.nih.gov/pubmed/34925364
http://dx.doi.org/10.3389/fimmu.2021.782891

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