DPP4 Regulates DHCR24-Mediated Cholesterol Biosynthesis to Promote Methotrexate Resistance in Gestational Trophoblastic Neoplastic Cells

Metabolic reprogramming could promote cellular adaptation in response to chemotherapeutic drugs in cancer cells. Herein, we aimed to characterize the metabolomic profiles regulated by Dipeptidyl Peptidase 4 (DPP4) in methotrexate (MTX)-resistant gestational trophoblastic neoplastic (GTN) cells. A to...

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Detalles Bibliográficos
Autores principales: Yuan, Weijie, Yong, Wenjing, Zhu, Jing, Shi, Dazun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675944/
https://www.ncbi.nlm.nih.gov/pubmed/34926239
http://dx.doi.org/10.3389/fonc.2021.704024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675944/
https://www.ncbi.nlm.nih.gov/pubmed/34926239
http://dx.doi.org/10.3389/fonc.2021.704024

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