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Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner

Estrogen receptor alpha (ERα) activation by estrogens prevents atheroma through its nuclear action, whereas plasma membrane-located ERα accelerates endothelial healing. The genetic deficiency of ERα was associated with a reduction in flow-mediated dilation (FMD) in one man. Here, we evaluated ex viv...

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Detalles Bibliográficos
Autores principales: Favre, Julie, Vessieres, Emilie, Guihot, Anne-Laure, Proux, Coralyne, Grimaud, Linda, Rivron, Jordan, Garcia, Manuela CL, Réthoré, Léa, Zahreddine, Rana, Davezac, Morgane, Fébrissy, Chanaelle, Adlanmerini, Marine, Loufrani, Laurent, Procaccio, Vincent, Foidart, Jean-Michel, Flouriot, Gilles, Lenfant, Françoise, Fontaine, Coralie, Arnal, Jean-François, Henrion, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8676342/
https://www.ncbi.nlm.nih.gov/pubmed/34842136
http://dx.doi.org/10.7554/eLife.68695