Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands

MicroRNAs (miRNAs) can serve as activation signals for membrane receptors, a recently discovered function that is independent of the miRNAs’ conventional role in post-transcriptional gene regulation. Here, we introduce a machine learning approach, BrainDead, to identify oligonucleotides that act as...

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Detalles Bibliográficos
Autores principales: Raden, Martin, Wallach, Thomas, Miladi, Milad, Zhai, Yuanyuan, Krüger, Christina, Mossmann, Zoé J., Dembny, Paul, Backofen, Rolf, Lehnardt, Seija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677043/
https://www.ncbi.nlm.nih.gov/pubmed/34241565
http://dx.doi.org/10.1080/15476286.2021.1940697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677043/
https://www.ncbi.nlm.nih.gov/pubmed/34241565
http://dx.doi.org/10.1080/15476286.2021.1940697

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