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Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands
MicroRNAs (miRNAs) can serve as activation signals for membrane receptors, a recently discovered function that is independent of the miRNAs’ conventional role in post-transcriptional gene regulation. Here, we introduce a machine learning approach, BrainDead, to identify oligonucleotides that act as...
Autores principales: | Raden, Martin, Wallach, Thomas, Miladi, Milad, Zhai, Yuanyuan, Krüger, Christina, Mossmann, Zoé J., Dembny, Paul, Backofen, Rolf, Lehnardt, Seija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677043/ https://www.ncbi.nlm.nih.gov/pubmed/34241565 http://dx.doi.org/10.1080/15476286.2021.1940697 |
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