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Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer’s disease

Alzheimer’s disease is characterized by cortical atrophy on MRI and abnormal depositions of amyloid-beta, phosphorylated-tau and inflammation pathologically. However, the relative contribution of these pathological hallmarks to cortical atrophy, a widely used MRI biomarker in Alzheimer’s disease, is...

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Detalles Bibliográficos
Autores principales: Frigerio, Irene, Boon, Baayla D C, Lin, Chen-Pei, Galis-de Graaf, Yvon, Bol, John, Preziosa, Paolo, Twisk, Jos, Barkhof, Frederik, Hoozemans, Jeroen J M, Bouwman, Femke H, Rozemuller, Annemieke J M, van de Berg, Wilma D J, Jonkman, Laura E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677327/
https://www.ncbi.nlm.nih.gov/pubmed/34927073
http://dx.doi.org/10.1093/braincomms/fcab281