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Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer’s disease
Alzheimer’s disease is characterized by cortical atrophy on MRI and abnormal depositions of amyloid-beta, phosphorylated-tau and inflammation pathologically. However, the relative contribution of these pathological hallmarks to cortical atrophy, a widely used MRI biomarker in Alzheimer’s disease, is...
Autores principales: | Frigerio, Irene, Boon, Baayla D C, Lin, Chen-Pei, Galis-de Graaf, Yvon, Bol, John, Preziosa, Paolo, Twisk, Jos, Barkhof, Frederik, Hoozemans, Jeroen J M, Bouwman, Femke H, Rozemuller, Annemieke J M, van de Berg, Wilma D J, Jonkman, Laura E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677327/ https://www.ncbi.nlm.nih.gov/pubmed/34927073 http://dx.doi.org/10.1093/braincomms/fcab281 |
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