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Vitamin B(12) Attenuates Acute Pancreatitis by Suppressing Oxidative Stress and Improving Mitochondria Dysfunction via CBS/SIRT1 Pathway

Acute pancreatitis is an inflammatory disorder of the pancreas associated with substantial morbidity and mortality, which is characterized by a rapid depletion of glutathione (GSH). Cysthionine-β-synthase (CBS) is a key coenzyme in GSH synthesis, and its deficiency is related to a variety of clinica...

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Detalles Bibliográficos
Autores principales: Yuan, Jiyan, Wei, Zeliang, Xin, Guang, Liu, Xubao, Zhou, Zongguang, Zhang, Yi, Yu, Xiuxian, Wan, Chengyu, Chen, Qingqiu, Zhao, Weiyu, Wang, Xueling, Dong, Yuman, Chen, Zhen, Chen, Xiaoting, Niu, Hai, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677375/
https://www.ncbi.nlm.nih.gov/pubmed/34925701
http://dx.doi.org/10.1155/2021/7936316