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Ellagic Acid Alleviates Rheumatoid Arthritis in Rats through Inhibiting MTA1/HDAC1-Mediated Nur77 Deacetylation

Ellagic acid (EA) was reported to play protective roles in rheumatoid arthritis (RA). It was found that the level of metastasis-associated gene 1 (MTA1)/histone deacetylase 1 (HDAC1) protein complex was downregulated by polyphenols in several human disorders. Notably, inhibition of MTA1 or HDAC1 has...

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Detalles Bibliográficos
Autores principales: Song, Huanjin, Wu, Hao, Dong, Jun, Huang, Sihua, Ye, Jintao, Liu, Ruoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677414/
https://www.ncbi.nlm.nih.gov/pubmed/34924813
http://dx.doi.org/10.1155/2021/6359652