TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia

TDP-43 nuclear depletion and concurrent cytoplasmic accumulation in vulnerable neurons is a hallmark feature of progressive neurodegenerative proteinopathies such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Cellular stress signalling and stress granule dynamics are now...

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Detalles Bibliográficos
Autores principales: Sidibé, Hadjara, Khalfallah, Yousra, Xiao, Shangxi, Gómez, Nicolás B, Fakim, Hana, Tank, Elizabeth M H, Di Tomasso, Geneviève, Bareke, Eric, Aulas, Anaïs, McKeever, Paul M, Melamed, Ze’ev, Destroimaisons, Laurie, Deshaies, Jade-Emmanuelle, Zinman, Lorne, Parker, J Alex, Legault, Pascale, Tétreault, Martine, Barmada, Sami J, Robertson, Janice, Vande Velde, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677511/
https://www.ncbi.nlm.nih.gov/pubmed/34115105
http://dx.doi.org/10.1093/brain/awab217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677511/
https://www.ncbi.nlm.nih.gov/pubmed/34115105
http://dx.doi.org/10.1093/brain/awab217

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