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Elevated peripheral blood neutrophil-to-lymphocyte ratio is associated with an immunosuppressive tumour microenvironment and decreased benefit of PD-1 antibody in advanced gastric cancer

BACKGROUND: Due to its limited efficacy and potential toxicity, anti-PD-1 monoclonal antibody is not suitable for all advanced gastric cancer (AGC) patients and predictive biomarkers identifying patients who can benefit from it are urgently needed. This study aimed to evaluate the predictive and pro...

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Detalles Bibliográficos
Autores principales: Ruan, Dan-Yun, Chen, Yan-Xing, Wei, Xiao-Li, Wang, Ying-Nan, Wang, Zi-Xian, Wu, Hao-Xiang, Xu, Rui-Hua, Yuan, Shu-Qiang, Wang, Feng-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677531/
https://www.ncbi.nlm.nih.gov/pubmed/34925853
http://dx.doi.org/10.1093/gastro/goab032