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Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury

Current evidence indicates that coronary microcirculation is a key target for protecting against cardiac ischemia–reperfusion (I/R) injury. Mitochondrial calcium uniporter (MCU) complex activation and mitochondrial calcium ([Ca(2+)](m)) overload are underlying mechanisms involved in cardiovascular d...

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Detalles Bibliográficos
Autores principales: Li, Su, Chen, Jinxiang, Liu, Muyin, Chen, Yuqiong, Wu, Yuan, Li, Qiyu, Ma, Teng, Gao, Jinfeng, Xia, Yan, Fan, Mengkang, Chen, Ao, Lu, Danbo, Su, Enyong, Xu, Fei, Chen, Zhangwei, Qian, Juying, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677646/
https://www.ncbi.nlm.nih.gov/pubmed/34914018
http://dx.doi.org/10.1007/s00395-021-00905-4