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A robotic pill for oral delivery of biotherapeutics: safety, tolerability, and performance in healthy subjects

Biotherapeutics are highly efficacious, but the pain and inconvenience of chronic injections lead to poor patient compliance and compromise effective disease management. Despite innumerable attempts, oral delivery of biotherapeutics remains unsuccessful due to their degradation in the gastrointestin...

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Detalles Bibliográficos
Autores principales: Dhalla, Arvinder K., Al-Shamsie, Ziad, Beraki, Simret, Dasari, Anvesh, Fung, Leonard C., Fusaro, Laura, Garapaty, Anusha, Gutierrez, Betsy, Gratta, Delia, Hashim, Mir, Horlen, Kyle, Karamchedu, Padma, Korupolu, Radhika, Liang, Eric, Ong, Chang, Owyang, Zachary, Salgotra, Vasudha, Sharma, Shilpy, Syed, Baber, Syed, Mansoor, Vo, April T., Abdul-Wahab, Radia, Wasi, Asad, Yamaguchi, Alyson, Yen, Shane, Imran, Mir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677648/
https://www.ncbi.nlm.nih.gov/pubmed/33604838
http://dx.doi.org/10.1007/s13346-021-00938-1