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A robotic pill for oral delivery of biotherapeutics: safety, tolerability, and performance in healthy subjects
Biotherapeutics are highly efficacious, but the pain and inconvenience of chronic injections lead to poor patient compliance and compromise effective disease management. Despite innumerable attempts, oral delivery of biotherapeutics remains unsuccessful due to their degradation in the gastrointestin...
Autores principales: | Dhalla, Arvinder K., Al-Shamsie, Ziad, Beraki, Simret, Dasari, Anvesh, Fung, Leonard C., Fusaro, Laura, Garapaty, Anusha, Gutierrez, Betsy, Gratta, Delia, Hashim, Mir, Horlen, Kyle, Karamchedu, Padma, Korupolu, Radhika, Liang, Eric, Ong, Chang, Owyang, Zachary, Salgotra, Vasudha, Sharma, Shilpy, Syed, Baber, Syed, Mansoor, Vo, April T., Abdul-Wahab, Radia, Wasi, Asad, Yamaguchi, Alyson, Yen, Shane, Imran, Mir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677648/ https://www.ncbi.nlm.nih.gov/pubmed/33604838 http://dx.doi.org/10.1007/s13346-021-00938-1 |
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