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Prognostic Stratification Based on HIF-1 Signaling for Evaluating Hypoxic Status and Immune Infiltration in Pancreatic Ductal Adenocarcinomas

Pancreatic ductal adenocarcinoma (PDAC) has a hypoxic and desmoplastic tumor microenvironment (TME), leading to treatment failure. We aimed to develop a prognostic classifier to evaluate hypoxia status and hypoxia-related molecular characteristics of PDAC. In this study, we classified PDAC into thre...

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Detalles Bibliográficos
Autores principales: Zhuang, Hongkai, Wang, Shujie, Chen, Bo, Zhang, Zedan, Ma, Zuyi, Li, Zhenchong, Liu, Chunsheng, Zhou, Zixuan, Gong, Yuanfeng, Huang, Shanzhou, Hou, Baohua, Chen, Yajin, Zhang, Chuanzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677693/
https://www.ncbi.nlm.nih.gov/pubmed/34925373
http://dx.doi.org/10.3389/fimmu.2021.790661