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Bacterial Quorum-Sensing Molecules as Promising Natural Inhibitors of Candida albicans Virulence Dimorphism: An In Silico and In Vitro Study

Farnesol, a self-secreted quorum-sensing molecule (QSM) of Candida albicans, has been known to limit yeast-to-hyphal transition by blocking the RAS1–cAMP–PKA pathway. In a similar fashion, certain bacterial QSMs have also been reported to be successful in attenuating C. albicans biofilm and hyphal f...

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Detalles Bibliográficos
Autores principales: Jothi, Ravi, Hari Prasath, Nagaiah, Gowrishankar, Shanmugaraj, Pandian, Shunmugiah Karutha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677694/
https://www.ncbi.nlm.nih.gov/pubmed/34926324
http://dx.doi.org/10.3389/fcimb.2021.781790