Preventive CCL2/CCR2 Axis Blockade Suppresses Osteoclast Activity in a Mouse Model of Rheumatoid Arthritis by Reducing Homing of CCR2(hi) Osteoclast Progenitors to the Affected Bone

Detailed characterization of medullary and extramedullary reservoirs of osteoclast progenitors (OCPs) is required to understand the pathophysiology of increased periarticular and systemic bone resorption in arthritis. In this study, we focused on identifying the OCP population specifically induced b...

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Detalles Bibliográficos
Autores principales: Flegar, Darja, Filipović, Maša, Šućur, Alan, Markotić, Antonio, Lukač, Nina, Šisl, Dino, Ikić Matijašević, Marina, Jajić, Zrinka, Kelava, Tomislav, Katavić, Vedran, Kovačić, Nataša, Grčević, Danka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677701/
https://www.ncbi.nlm.nih.gov/pubmed/34925336
http://dx.doi.org/10.3389/fimmu.2021.767231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677701/
https://www.ncbi.nlm.nih.gov/pubmed/34925336
http://dx.doi.org/10.3389/fimmu.2021.767231

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