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Targeting PI3K/Akt signal transduction for cancer therapy

The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a crucial role in various cellular processes and is aberrantly activated in cancers, contributing to the occurrence and progression of tumors. Examining the upstream and downstream nodes of this pathway could allow full elucidation of its fu...

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Detalles Bibliográficos
Autores principales: He, Yan, Sun, Miao Miao, Zhang, Guo Geng, Yang, Jing, Chen, Kui Sheng, Xu, Wen Wen, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677728/
https://www.ncbi.nlm.nih.gov/pubmed/34916492
http://dx.doi.org/10.1038/s41392-021-00828-5