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Targeting PI3K/Akt signal transduction for cancer therapy
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a crucial role in various cellular processes and is aberrantly activated in cancers, contributing to the occurrence and progression of tumors. Examining the upstream and downstream nodes of this pathway could allow full elucidation of its fu...
Autores principales: | He, Yan, Sun, Miao Miao, Zhang, Guo Geng, Yang, Jing, Chen, Kui Sheng, Xu, Wen Wen, Li, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677728/ https://www.ncbi.nlm.nih.gov/pubmed/34916492 http://dx.doi.org/10.1038/s41392-021-00828-5 |
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