Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice

A novel synthetic compound from the 2-benzoyl-6-benzylidenecyclohexanone analogue, namely 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol (BBHC), showed pronounced nitric oxide inhibition in IFN-γ/LPS-induced RAW 264.7 cells. Based on this previous finding, our present study aimed to inves...

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Detalles Bibliográficos
Autores principales: Ong, Hui Ming, Azmi, Ahmad Farhan Ahmad, Leong, Sze Wei, Abas, Faridah, Perimal, Enoch Kumar, Farouk, Ahmad Akira Omar, Israf, Daud Ahmad, Sulaiman, Mohd Roslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677729/
https://www.ncbi.nlm.nih.gov/pubmed/34916536
http://dx.doi.org/10.1038/s41598-021-02961-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677729/
https://www.ncbi.nlm.nih.gov/pubmed/34916536
http://dx.doi.org/10.1038/s41598-021-02961-1

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