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In vitro functional analysis of gRNA sites regulating assembly of hepatitis B virus

The roles of RNA sequence/structure motifs, Packaging Signals (PSs), for regulating assembly of an HBV genome transcript have been investigated in an efficient in vitro assay containing only core protein (Cp) and RNA. Variants of three conserved PSs, within the genome of a strain not used previously...

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Detalles Bibliográficos
Autores principales: Patel, Nikesh, Clark, Sam, Weiß, Eva U., Mata, Carlos P., Bohon, Jen, Farquhar, Erik R., Maskell, Daniel P., Ranson, Neil A., Twarock, Reidun, Stockley, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677749/
https://www.ncbi.nlm.nih.gov/pubmed/34916604
http://dx.doi.org/10.1038/s42003-021-02897-2