TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4

Metastasis remains the major obstacle to improved survival for colorectal cancer (CRC) patients. Dysregulation of N6-methyladenosine (m6A) is causally associated with the development of metastasis through poorly understood mechanisms. Here, we report that METTL14, a key component of m6A methylation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hao, Wei, Wei, Zhang, Zhong-Yuan, Liu, Yao, Shi, Bin, Zhong, Wen, Zhang, Hou-Shun, Fang, Xin, Sun, Chun-Lei, Wang, Jia-Bei, Liu, Lian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677753/
https://www.ncbi.nlm.nih.gov/pubmed/34916487
http://dx.doi.org/10.1038/s41419-021-04459-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677753/
https://www.ncbi.nlm.nih.gov/pubmed/34916487
http://dx.doi.org/10.1038/s41419-021-04459-0

Ejemplares similares