Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome

Rett syndrome (RTT) is a regressive neurodevelopmental disorder in girls, characterized by multisystem complications including gut dysbiosis and altered metabolism. While RTT is known to be caused by mutations in the X-linked gene MECP2, the intermediate molecular pathways of progressive disease phe...

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Detalles Bibliográficos
Autores principales: Neier, Kari, Grant, Tianna E., Palmer, Rebecca L., Chappell, Demario, Hakam, Sophia M., Yasui, Kendra M., Rolston, Matt, Settles, Matthew L., Hunter, Samuel S., Madany, Abdullah, Ashwood, Paul, Durbin-Johnson, Blythe, LaSalle, Janine M., Yasui, Dag H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677842/
https://www.ncbi.nlm.nih.gov/pubmed/34916612
http://dx.doi.org/10.1038/s42003-021-02915-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677842/
https://www.ncbi.nlm.nih.gov/pubmed/34916612
http://dx.doi.org/10.1038/s42003-021-02915-3

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