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Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome
Rett syndrome (RTT) is a regressive neurodevelopmental disorder in girls, characterized by multisystem complications including gut dysbiosis and altered metabolism. While RTT is known to be caused by mutations in the X-linked gene MECP2, the intermediate molecular pathways of progressive disease phe...
Autores principales: | Neier, Kari, Grant, Tianna E., Palmer, Rebecca L., Chappell, Demario, Hakam, Sophia M., Yasui, Kendra M., Rolston, Matt, Settles, Matthew L., Hunter, Samuel S., Madany, Abdullah, Ashwood, Paul, Durbin-Johnson, Blythe, LaSalle, Janine M., Yasui, Dag H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677842/ https://www.ncbi.nlm.nih.gov/pubmed/34916612 http://dx.doi.org/10.1038/s42003-021-02915-3 |
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