R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability

Transcription poses a threat to genomic stability through the formation of R-loops that can obstruct progression of replication forks. R-loops are three-stranded nucleic acid structures formed by an RNA–DNA hybrid with a displaced non-template DNA strand. We developed RNA–DNA Proximity Proteomics to...

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Detalles Bibliográficos
Autores principales: Mosler, Thorsten, Conte, Francesca, Longo, Gabriel M. C., Mikicic, Ivan, Kreim, Nastasja, Möckel, Martin M., Petrosino, Giuseppe, Flach, Johanna, Barau, Joan, Luke, Brian, Roukos, Vassilis, Beli, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677849/
https://www.ncbi.nlm.nih.gov/pubmed/34916496
http://dx.doi.org/10.1038/s41467-021-27530-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677849/
https://www.ncbi.nlm.nih.gov/pubmed/34916496
http://dx.doi.org/10.1038/s41467-021-27530-y

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