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R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability

Transcription poses a threat to genomic stability through the formation of R-loops that can obstruct progression of replication forks. R-loops are three-stranded nucleic acid structures formed by an RNA–DNA hybrid with a displaced non-template DNA strand. We developed RNA–DNA Proximity Proteomics to...

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Detalles Bibliográficos
Autores principales:	Mosler, Thorsten, Conte, Francesca, Longo, Gabriel M. C., Mikicic, Ivan, Kreim, Nastasja, Möckel, Martin M., Petrosino, Giuseppe, Flach, Johanna, Barau, Joan, Luke, Brian, Roukos, Vassilis, Beli, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677849/ https://www.ncbi.nlm.nih.gov/pubmed/34916496 http://dx.doi.org/10.1038/s41467-021-27530-y

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