Untangling the KRAS mutated lung cancer subsets and its therapeutic implications

The Kirsten rat sarcoma virus transforming protein (KRAS) mutations (predominate in codons 12, 13, and 61) and genomically drive nearly one-third of lung carcinomas. These mutations have complex functions in tumorigenesis, and influence the tumor response to chemotherapy and tyrosine kinase inhibito...

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Detalles Bibliográficos
Autores principales: Ritu, Kulshrestha, Kumar, Pawan, Singh, Amit, Nupur, K., Spalgias, Sonam, Mrigpuri, Parul, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677854/
https://www.ncbi.nlm.nih.gov/pubmed/34918209
http://dx.doi.org/10.1186/s43556-021-00061-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677854/
https://www.ncbi.nlm.nih.gov/pubmed/34918209
http://dx.doi.org/10.1186/s43556-021-00061-0

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