Improving Immunotherapy Efficacy in Soft-Tissue Sarcomas: A Biomarker Driven and Histotype Tailored Review

Anti-PD-(L)1 therapies yield a disappointing response rate of 15% across soft-tissue sarcomas, even if some subtypes benefit more than others. The proportions of TAMs and TILs in their tumor microenvironment are variable, and this heterogeneity correlates to histotype. Tumors with a richer CD8+ T ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Roulleaux Dugage, Matthieu, Nassif, Elise F., Italiano, Antoine, Bahleda, Rastislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678134/
https://www.ncbi.nlm.nih.gov/pubmed/34925348
http://dx.doi.org/10.3389/fimmu.2021.775761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678134/
https://www.ncbi.nlm.nih.gov/pubmed/34925348
http://dx.doi.org/10.3389/fimmu.2021.775761

Ejemplares similares