Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes

Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has been observed within the nuclei of neurons, but there i...

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Detalles Bibliográficos
Autores principales: Montalbano, Mauro, Jaworski, Elizabeth, Garcia, Stephanie, Ellsworth, Anna, McAllen, Salome, Routh, Andrew, Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678415/
https://www.ncbi.nlm.nih.gov/pubmed/34924950
http://dx.doi.org/10.3389/fnmol.2021.742790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678415/
https://www.ncbi.nlm.nih.gov/pubmed/34924950
http://dx.doi.org/10.3389/fnmol.2021.742790

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