Oxytocin Protects Against Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting PI3K/AKT Pathway via a lncRNA GAS5/miR-375-3p/KLF4-Dependent Mechanism

Cardiac hypertrophy is caused by cardiac volume or pressure overload conditions and ultimately leads to contractile dysfunction and heart failure. Oxytocin (OT), an endocrine nonapeptide, has been identified as a cardiovascular homeostatic hormone with anti-hypertrophic effects. However, the underly...

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Detalles Bibliográficos
Autores principales: Yang, Yuqiao, Wang, Zhuoran, Yao, Mengran, Xiong, Wei, Wang, Jun, Fang, Yu, Yang, Wei, Jiang, Haixia, Song, Ning, Liu, Lan, Qian, Jinqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678504/
https://www.ncbi.nlm.nih.gov/pubmed/34925023
http://dx.doi.org/10.3389/fphar.2021.766024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678504/
https://www.ncbi.nlm.nih.gov/pubmed/34925023
http://dx.doi.org/10.3389/fphar.2021.766024

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