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Effects of simeprevir on the replication of SARS-CoV-2 in vitro and in transgenic hACE2 mice

In a bid to contain the current COVID-19 (coronavirus disease 2019) pandemic, various countermeasures have been applied. To date, however, there is a lack of an effective drug for the treatment of COVID-19. Through molecular modelling studies, simeprevir, a protease inhibitor approved for the manage...

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Detalles Bibliográficos
Autores principales: Muturi, Elishiba, Hong, Wei, Li, Junhua, Yang, Wan, He, Jin, Wei, Hongping, Yang, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd and International Society of Antimicrobial Chemotherapy. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679493/
https://www.ncbi.nlm.nih.gov/pubmed/34929295
http://dx.doi.org/10.1016/j.ijantimicag.2021.106499