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Effects of simeprevir on the replication of SARS-CoV-2 in vitro and in transgenic hACE2 mice
In a bid to contain the current COVID-19 (coronavirus disease 2019) pandemic, various countermeasures have been applied. To date, however, there is a lack of an effective drug for the treatment of COVID-19. Through molecular modelling studies, simeprevir, a protease inhibitor approved for the manage...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd and International Society of Antimicrobial Chemotherapy.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679493/ https://www.ncbi.nlm.nih.gov/pubmed/34929295 http://dx.doi.org/10.1016/j.ijantimicag.2021.106499 |