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LPA(1) signaling drives Schwann cell dedifferentiation in experimental autoimmune neuritis

BACKGROUND: Lysophosphatidic acid (LPA) is a pleiotropic lipid messenger that addresses at least six specific G-protein coupled receptors. Accumulating evidence indicates a significant involvement of LPA in immune cell regulation as well as Schwann cell physiology, with potential relevance for the p...

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Detalles Bibliográficos
Autores principales: Szepanowski, Fabian, Winkelhausen, Maximilian, Steubing, Rebecca D., Mausberg, Anne K., Kleinschnitz, Christoph, Stettner, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680309/
https://www.ncbi.nlm.nih.gov/pubmed/34920725
http://dx.doi.org/10.1186/s12974-021-02350-5