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The First Evaluation of a Geroscience Biomarker Index (TAME-BI) in a Trial of Caloric Restriction and Exercise

We leveraged the WF OAIC biorepository to measure a consensus-derived panel of blood-based biomarkers of aging and constructed a geroscience-guided biomarker index (TAME-BI), testing it for the first time in a clinical trial. We measured IL-6, TNF-α-receptor-I, growth differentiating factor-15, cyst...

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Detalles Bibliográficos
Autores principales: Justice, Jamie, Espeland, Mark, Houston, Denise, Kritchevsky, Stephen, Nicklas, Barbara, Pajewski, Nicholas, Kitzman, Dalane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680521/
http://dx.doi.org/10.1093/geroni/igab046.299