Age-Related Neuroprotection by Dietary Restriction Requires OXR1-Mediated Retromer Function

Dietary restriction (DR) is the most robust method to delay aging and the onset of neurogenerative disorders across multiple species, though the mechanisms behind this phenomenon remain unknown. To elucidate how DR mediates lifespan extension, we analyzed natural genetic variants that associate with...

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Detalles Bibliográficos
Autores principales: Wilson, Kenneth, Bar, Sudipta, Brownridge, George, Beck, Jennifer, Brem, Rachel, Bellen, Hugo, Ellerby, Lisa, Kapahi, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680557/
http://dx.doi.org/10.1093/geroni/igab046.2151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680557/
http://dx.doi.org/10.1093/geroni/igab046.2151

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