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Chronic Exposure to Youthful Circulation Leads to Epigenetic Reprogramming and Lifespan Extension

Heterochronic parabiosis is a powerful rejuvenation model in aging research. Due to limitations in the duration of blood sharing and/or physical attachment, it is currently unclear if parabiosis retards the molecular signatures of aging or affects healthspan/lifespan in the mouse. Here, we describe...

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Detalles Bibliográficos
Autores principales: Zhang, Bohan, Lee, David, Tyshkovskiy, Alexander, Bareja, Akshay, Kerepesi, Csaba, Horvath, Steve, Gladyshev, Vadim, White, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680621/
http://dx.doi.org/10.1093/geroni/igab046.2551