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Phenylboronic Acid-Modified Polyamidoamine Mediated the Transfection of Polo-Like Kinase-1 siRNA to Achieve an Anti-Tumor Efficacy

BACKGROUND: The construction of tumor-targeting carriers with favorable transfection efficiency was of great significance to achieve the tumor gene therapy. The phenylboronic acid-modified polyamidoamine (namely PP) was employed as a carrier for the delivery of Polo-like kinase-1 siRNA (siPlk-1), in...

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Detalles Bibliográficos
Autores principales: Gong, Gu, Tang, Xiuhui, Zhang, Jiayuan, Liang, Xiao, Yang, Jiebing, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680781/
https://www.ncbi.nlm.nih.gov/pubmed/34934312
http://dx.doi.org/10.2147/IJN.S329433