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An Evolving Role for the Long Non-Coding RNA H19 in Aging and Senescence

The long non-coding RNA (lncRNA) H19 is a maternally imprinted gene transcript that, in conjunction with the neighboring Igf2 gene, is critical in controlling embryonic growth. Loss of H19 results in fetal overgrowth associated with Beckwith Weidemann syndrome, while elevated H19 occurs in human can...

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Detalles Bibliográficos
Autores principales: Potnis, Manali, Sell, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8680796/
http://dx.doi.org/10.1093/geroni/igab046.2153