Cargando…

Sertraline repositioning: an overview of its potential use as a chemotherapeutic agent after four decades of tumor reversal studies

Sertraline hydrochloride is a first-line antidepressant with potential antineoplastic properties because of its structural similarity with other drugs capable to inhibit the translation-controlled tumor protein (TCTP), a biomolecule involved in cell proliferation. Recent studies suggest it could be...

Descripción completa

Detalles Bibliográficos
Autores principales: Baú-Carneiro, João Luiz, Akemi Guirao Sumida, Isabela, Gallon, Malu, Zaleski, Tânia, Boia-Ferreira, Marianna, Bridi Cavassin, Francelise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681026/
https://www.ncbi.nlm.nih.gov/pubmed/34911014
http://dx.doi.org/10.1016/j.tranon.2021.101303