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Sertraline repositioning: an overview of its potential use as a chemotherapeutic agent after four decades of tumor reversal studies
Sertraline hydrochloride is a first-line antidepressant with potential antineoplastic properties because of its structural similarity with other drugs capable to inhibit the translation-controlled tumor protein (TCTP), a biomolecule involved in cell proliferation. Recent studies suggest it could be...
Autores principales: | Baú-Carneiro, João Luiz, Akemi Guirao Sumida, Isabela, Gallon, Malu, Zaleski, Tânia, Boia-Ferreira, Marianna, Bridi Cavassin, Francelise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681026/ https://www.ncbi.nlm.nih.gov/pubmed/34911014 http://dx.doi.org/10.1016/j.tranon.2021.101303 |
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