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Genes Involved in Physiological Dysregulation and Decline in Resilience: Role in Alzheimer’s Disease

Our recent GWAS of a composite measure of physiological dysregulation (PD) in the Long Life Family Study (LLFS) found that the top genes associated with age-related changes in PD are involved in biological pathways relevant to maintaining neural networks and brain resilience. In our prior work, PD i...

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Detalles Bibliográficos
Autores principales: Ukraintseva, Svetlana, Bagley, Olivia, Duan, Hongzhe, Wu, Deqing, Akushevich, Igor, Kulminski, Alexander, Yashin, Anatoliy, Arbeev, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681088/
http://dx.doi.org/10.1093/geroni/igab046.2223