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Targeting kynurenine metabolism to reduce inflammation and enhance stress response during aging
Aberrant kynurenine pathway metabolism is increasingly linked to aging and age-associated disease. Kynurenine metabolic activity increases with age and becomes dysregulated during various forms of age-associated pathology in humans. By manipulating one or more kynurenine pathway enzymes and metaboli...
Autores principales: | Sutphin, George, Dang, Hope, Espejo, Luis, Castro-Portuguez, Raul, Hull, Bradford, Meyers, Jeremy, Turner, Emily, DeNicola, Destiny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681472/ http://dx.doi.org/10.1093/geroni/igab046.2565 |
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