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A Randomized Placebo-Controlled Trial of Metformin for Frailty Prevention in Older Adults

Frailty is a progressive physical decline leading to higher morbidity and mortality in older adults. Previous studies have demonstrated shared mechanisms between insulin resistance, inflammation, and frailty. The purpose of this trial is to determine whether metformin prevents frailty in non-frail,...

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Detalles Bibliográficos
Autores principales: Tavabi, Amir, Wang, Chen-pin, Michalek, Joel, Cortes, Tiffany, Leonard, Ethan, Powers, Becky, Musi, Nicolas, Espinoza, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681623/
http://dx.doi.org/10.1093/geroni/igab046.2991