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α-Conotoxin TxIB Inhibits Development of Morphine-Induced Conditioned Place Preference in Mice via Blocking α6β2* Nicotinic Acetylcholine Receptors

Morphine, the main component of opium, is a commonly used analgesic in clinical practice, but its abuse potential limits its clinical application. Nicotinic acetylcholine receptors (nAChRs) in the mesolimbic circuitry play an important role in the rewarding effects of abused drugs. Previous studies...

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Detalles Bibliográficos
Autores principales: Li, Xiaodan, Xiong, Jian, Zhang, Baojian, Zhangsun, Dongting, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8681874/
https://www.ncbi.nlm.nih.gov/pubmed/34925031
http://dx.doi.org/10.3389/fphar.2021.772990