A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences

Exposure to early-life adversity (ELA) is associated with several neuropsychiatric conditions, including major depressive disorder, yet causality is difficult to establish in humans. Recent work in rodents has implicated impaired reward circuit signaling in anhedonic-like behavior after ELA exposure...

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Detalles Bibliográficos
Autores principales: Kangas, Brian D., Short, Annabel K., Luc, Oanh T., Stern, Hal S., Baram, Tallie Z., Pizzagalli, Diego A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682039/
https://www.ncbi.nlm.nih.gov/pubmed/34921225
http://dx.doi.org/10.1038/s41386-021-01250-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682039/
https://www.ncbi.nlm.nih.gov/pubmed/34921225
http://dx.doi.org/10.1038/s41386-021-01250-9

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