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Complexities in the role of acetylation dynamics in modifying inducible gene activation parameters

High levels of histone acetylation are associated with the regulatory elements of active genes, suggesting a link between acetylation and gene activation. We revisited this model, in the context of EGF-inducible gene expression and found that rather than a simple unifying model, there are two broad...

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Detalles Bibliográficos
Autores principales: Carrera, Samantha, O’Donnell, Amanda, Li, Yaoyong, Nowicki-Osuch, Karol, Yang, Shen-Hsi, Baker, Syed Murtuza, Spiller, David, Sharrocks, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682737/
https://www.ncbi.nlm.nih.gov/pubmed/34850951
http://dx.doi.org/10.1093/nar/gkab1176