Constrained peptides mimic a viral suppressor of RNA silencing

The design of high-affinity, RNA-binding ligands has proven very challenging. This is due to the unique structural properties of RNA, often characterized by polar surfaces and high flexibility. In addition, the frequent lack of well-defined binding pockets complicates the development of small molecu...

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Detalles Bibliográficos
Autores principales: Kuepper, Arne, McLoughlin, Niall M, Neubacher, Saskia, Yeste-Vázquez, Alejandro, Collado Camps, Estel, Nithin, Chandran, Mukherjee, Sunandan, Bethge, Lucas, Bujnicki, Janusz M, Brock, Roland, Heinrichs, Stefan, Grossmann, Tom N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682738/
https://www.ncbi.nlm.nih.gov/pubmed/34871435
http://dx.doi.org/10.1093/nar/gkab1149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682738/
https://www.ncbi.nlm.nih.gov/pubmed/34871435
http://dx.doi.org/10.1093/nar/gkab1149

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