Coordination of -1 programmed ribosomal frameshifting by transcript and nascent chain features revealed by deep mutational scanning

Programmed ribosomal frameshifting (PRF) is a translational recoding mechanism that enables the synthesis of multiple polypeptides from a single transcript. During translation of the alphavirus structural polyprotein, the efficiency of −1PRF is coordinated by a ‘slippery’ sequence in the transcript,...

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Detalles Bibliográficos
Autores principales: Carmody, Patrick J, Zimmer, Matthew H, Kuntz, Charles P, Harrington, Haley R, Duckworth, Kate E, Penn, Wesley D, Mukhopadhyay, Suchetana, Miller, Thomas F, Schlebach, Jonathan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682741/
https://www.ncbi.nlm.nih.gov/pubmed/34871407
http://dx.doi.org/10.1093/nar/gkab1172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682741/
https://www.ncbi.nlm.nih.gov/pubmed/34871407
http://dx.doi.org/10.1093/nar/gkab1172

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