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Coordination of -1 programmed ribosomal frameshifting by transcript and nascent chain features revealed by deep mutational scanning

Programmed ribosomal frameshifting (PRF) is a translational recoding mechanism that enables the synthesis of multiple polypeptides from a single transcript. During translation of the alphavirus structural polyprotein, the efficiency of −1PRF is coordinated by a ‘slippery’ sequence in the transcript,...

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Detalles Bibliográficos
Autores principales:	Carmody, Patrick J, Zimmer, Matthew H, Kuntz, Charles P, Harrington, Haley R, Duckworth, Kate E, Penn, Wesley D, Mukhopadhyay, Suchetana, Miller, Thomas F, Schlebach, Jonathan P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682741/ https://www.ncbi.nlm.nih.gov/pubmed/34871407 http://dx.doi.org/10.1093/nar/gkab1172

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