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DNA methylation variation along the cancer epigenome and the identification of novel epigenetic driver events

While large-scale studies applying various statistical approaches have identified hundreds of mutated driver genes across various cancer types, the contribution of epigenetic changes to cancer remains more enigmatic. This is partly due to the fact that certain regions of the cancer genome, due to th...

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Detalles Bibliográficos
Autores principales: Heery, Richard, Schaefer, Martin H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682778/
https://www.ncbi.nlm.nih.gov/pubmed/34871444
http://dx.doi.org/10.1093/nar/gkab1167